3-CARBOXY-4-METHOXYPHENYLBORONIC ACID

3-CARBOXY-4-METHOXYPHENYLBORONIC ACID - Names and Identifiers

Name	5-borono-2-methoxy-benzoic acid
Synonyms	5-BORONO-2-METHOXYBENZOIC ACID 5-borono-2-methoxy-benzoic acid 5-BORONO-2-METHOXYPHENYLBORONIC ACID 3-CARBOXY-4-METHOXYPHENYLBORONIC ACID 3-Carboxy-4-methoxyphenylboronic acid 3-Carboxy-4-Methoxybenzeneboronic Acid 3-Carboxy-4-methoxybenzeneboronic acid 5-(dihydroxyboryl)-2-Methoxybenzoic acid 5-Borono-2-methoxybenzoic acid, 4-Borono-2-carboxyanisole
CAS	913836-12-1
InChI	InChI=1/C8H9BO5/c1-14-7-3-2-5(9(12)13)4-6(7)8(10)11/h2-4,12-13H,1H3,(H,10,11)

3-CARBOXY-4-METHOXYPHENYLBORONIC ACID - Physico-chemical Properties

Molecular Formula	C8H9BO5
Molar Mass	195.97
Density	1.39±0.1 g/cm3(Predicted)
Melting Point	176-177
Boling Point	442.5±55.0 °C(Predicted)
Flash Point	221.4°C
Vapor Presure	1.31E-08mmHg at 25°C
pKa	4.10±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.568

3-CARBOXY-4-METHOXYPHENYLBORONIC ACID - Risk and Safety

Hazard Symbols	Xi - Irritant
Hazard Note	Irritant

3-CARBOXY-4-METHOXYPHENYLBORONIC ACID - Introduction

Acid is an organic compound with the formula C8H9BO4. The following is an introduction to its nature, use, preparation and safety information:

1. nature:
-Appearance: acid is a white crystalline solid.
-Solubility: It is less soluble in water and more soluble in organic solvents.
-Melting point: Its melting point is about 190-192 degrees Celsius.

2. use:
-Chemical research: acid is often used as an important reagent in organic synthesis, such as the reagent in the substitution reaction of benzene ring and the ligand of transition metal complex.
-Drug research: It is also widely used in the field of drug research, such as the development of anti-cancer drugs.

3. preparation method:
-The common preparation method of acid is obtained by the reaction of p-methoxybenzoic acid and triphenylketonate borate. Reaction conditions often require an anhydrous and oxygen-free environment, commonly used solvents such as tetrahydrofuran or dimethylformamide.

4. Safety Information:
-The toxicity of acid is low, but it is still necessary to pay attention to correct operation and avoid contact with eyes, skin and administration.
-Wear appropriate personal protective equipment, such as lab gloves and goggles, during use.
-Should be stored properly, away from ignition and oxidizing agents.
-Follow safe practices when handling the compound and dispose of waste properly.

Last Update：2024-04-09 02:00:49